[English]
Imagine
[Music]
a crisp fall evening. The sky a canvas
of amber and violet. Suddenly thousands
of starings appear performing a
breathtaking aerial ballet. This ballet
is called emeration.
It's a stunning natural phenomena that
holds the secret to the very essence of
life.
I am a physicist and I see something
very profound in the flight of these
starings. I see fundamental principles
that govern not just these birds but all
of life from the tiniest of cells to the
vastest ecosystems.
So where do we go from here? Let me take
you on a journey to discover the physics
of non-equilibrium systems like these
starings that can account for the
phenomena of life.
To understand the world around us, we
need to grasp two fundamental concepts,
equilibrium and non-equilibrium.
Let's start with the concept of
equilibrium, a state of balance and
stability. To illustrate this, let's
consider a simple bar magnet. If we
could zoom in, we would see that this
bar magnet is made up of countless tiny
domains, each like a compass needle. In
an ordinary piece of iron, these tiny
compasses point in random directions.
But when we apply an external magnetic
field, something remarkable happens.
these domains begin to align.
This alignment process is an example of
what we call symmetry breaking in
physics.
Initially there is no preferred
direction for the domains. This is a
symmetry. But when we apply an external
magnetic field, this symmetry breaks.
The system chooses a specific direction
by aligning the domains. And once
aligned, these domains reach a state of
equilibrium, stable, predictable,
unchanging.
If we were to film these domains and
play the movie backward, it would almost
look identical to the forward version.
This is a hallmark of an equilibrium
state. Time loses its direction. But
this state, this state of equilibrium is
not actually where life thrives. In
fact, it is the antithesis of life. Life
in all its messy, complex, beautiful
glory exists, far from equilibrium.
Now with this understanding of
equilibrium, let's shift our focus to
where life truly thrives, far from
equilibrium. And let's return to our
starings, a much more complex and
dynamic example.
You can think of each bird in this
aerial ballet as a flying living compass
needle.
Just as the alignment of our magnetic
domains led to the emergence of a
macroscopic magnetic field, these birds
align their velocities with their
neighbors. But here's a crucial
difference. This alignment is ever
changing, responding moment by moment to
the movement of neighboring birds. The
result is a mesmerizing display of
collective behavior that seems to defy
explanation.
Some people will see a thrashing
serpent, some a billowing cloud, or even
a pulsing heart in their formation. The
flock moves as one, yet it is composed
of thousands of individual decision
makers. It's a dynamic living system
that never settles into the quiet
equilibrium of our bar magnet. Instead,
it remains in constant motion,
perpetually consuming energy to maintain
its intricate dance. This perpetual
motion, this seizeless consumption of
energy is what we mean by
non-equilibrio.
And here is where it truly gets
fascinating. It is in this state of
equilibrium that we find the seeds of
life's beauty and complexity.
Now with this understanding of
non-equilibrium, let's return to the
idea of symmetry breaking. In
non-equilibrium systems like our stling
flock, symmetry breaking is not a
one-time event leading into a stable
state. Instead, it's an ongoing process
driven by the constant flow of energy
and matter. We see a cascade of symmetry
breaking events. Each break in symmetry
creates new possibilities, new patterns,
new structures. It's like a neverending
game of dominoes where each fallen piece
triggers new and unexpected
arrangements.
This continuous symmetry breaking in
non-equilibrium systems is what allows
for the incredible diversity and
adaptability of life. It's why living
systems can respond to their
environment, evolve, and create
increasingly complex structures.
Let's combine these ideas,
non-equilibrium and symmetry breaking,
and revisit our stling murmmoration. The
starling murmmoration is a perfect
example of emergence in a
non-equilibrium system.
Just as the alignment of the microscopic
domains in our bar magnet led to the
emergence of a macroscopic magnetic
field, the coordination among individual
starings lead to the emergence of the
flock's complex and fluid-like behavior.
But here is the crucial difference. In
the magnet, emergence leads to a stable
equilibrium state. In the flock,
emergence is dynamic, ongoing.
The behavior of the flock continuously
emerges from the interactions of
individual birds. Yet it also guides
those same individuals creating a
feedback loop that maintains this system
far from equilibrium.
This dynamic emergence is a feature of
living systems. And it is the same
principle that applies to us all. It
would allows for a collection of cells
to become a thinking feeling human being
or a group of humans to form complex
societies. In each case, the behavior of
the whole emerges from yet it also
guides the behavior of its parts.
Okay, we have seen non-equilibrium on
the grand scale of murmmoration. But
this state isn't just confined to the
macroscopic.
In fact, the same principles that we
observe in our murmmoration are
universal manifesting across all scales
of life. So let's zoom in from our
murmmoration to something much smaller
yet no less wondrous, a single living
cell. Within this microscopic world, a
drama unfolds that mirrors the same
dance that we see in the sky above. In
my lab, using advanced microscopes, we
can watch proteins, the building blocks
of life, organized into waves and
spirals of activity that ripple across
the surface of a dividing cell.
Just as each stling responds to its
neighbors to create the sweeping
patterns of mermoration, these proteins
interact with their molecular neighbors
to create patterns that guide the
development of life itself.
What's truly remarkable is that we can
use the same principles of
non-equilibrium physics to describe
these intricate biological processes.
For example, we have discovered that
these protein spirals behave like
charged particles with the core of each
spiral corresponding to either a
positive or negative charge depending on
their rotation. And just like electric
charges organize electric fields, these
focal points of protein activity
orchestrate the developmental processes
across an entire O site. Oh, these
patterns, they never cease to amaze me.
As we watch these protein patterns dance
across the surface of a dividing cell,
we witness something even more
fundamental. Another symmetry that life
breaks and that is the symmetry of time
itself. Remember our bar magnet in its
equilibrium state time loses its
direction. We could play the movie of
the magnet forward and backward and it
would look almost identical.
But in the non-equilibrium world of
living systems, time is an arrow. It has
a clear irreversible direction. Think of
our murmmoration. You can easily imagine
the video of memoration played in
reverse. But it would immediately look
wrong, unnatural.
Every wing bit of a starling, every cell
division in a developing embryo and
every heartbeat in your chest is a step
forward in time that cannot be undone.
Let me tell you the most remarkable
thing. We can show that this arrow of
time is mathematically related to the
flow of energy in living systems. In
other words, direction of time arises
from energy dissipation or arises from
how far from equilibrium your system is.
We can quantify this using a
thermodynamic concept termed entropy.
Entropy simply put is a measure of
disorder. In living systems which
continuously exchange energy and matter
with the environment, higher energy
flows means higher entropy production
and more irreversible processes. And in
fact, my group's experiments with these
protein patterns have confirmed this.
Now, this irreversibility
is what shapes how we perceive time. And
what's truly remarkable is that living
systems can create order and complexity
while adding to the universe's overall
increase in entropy.
Okay, we have seen this fundamental
principles of non-equilibrium from cells
to starings. You might be wondering, so
what? How does this change our view of
the world around us? When we embrace
this dynamic view of life, we start
asking new questions and exploring new
possibilities.
For example, can we use this fundamental
principles of non-equilibrium physics to
design new materials that are smarter
and more adaptable?
Could studying energy flows in
ecosystems help us discover more
sustainable ways to produce and use
energy?
And if life is truly a phenomena of
non-equilibrium physics, should we look
for the origins of life in pro in places
where fluxes and energy flows create the
potential for complexity.
And by thinking this way, we open
ourselves to discovering new forms of
life or lifelike processes that we
haven't even imagined.
And you know what's the most amazing
part? We don't have to look far to see
these fundamental processes in action.
Our own planet is full of diversity that
arises from these fundamental processes.
Take a coral reef for example. It's a
delicate balance where countless species
find their way within the flow of energy
and matter. Or think about human brain
where billions of neurons fire in
coordinated patterns to create what we
call consciousness.
Even our societies with their complex
economic and social structures could be
understood through the lens of
non-equilibrium physics.
As our journey comes to an end, let's
return once more to our starings seen
through new eyes. As the last light
fades, they bring their ballet to the
final curtain, settling gracefully into
their roosts. Through them, we see how
energy drives matter to self-organize,
how breaking symmetries create
diversity, and how time's arrow arises
from the processes that drive life.
I will never forget that moment in my
lab, watching through the microscope as
the protein patterns ripple across the
surface of the dividing cell with energy
flowing and conducting this ballet
through time. That moment fundamentally
shifted my perspective. I realized that
life isn't about reaching equilibrium.
It's about maintaining this dance far
from it. And it is in this constant
flux, this journey of becoming that the
true wonder of existence lies. A dance
we're all part of every moment.
Thank you.